Fluorescent Tracking of Yeast Division Clarifies the Essential Role of Spleen Tyrosine Kinase in the Intracellular Control of Candida glabrata in Macrophages

Macrophages play a critical role in the elimination of fungal pathogens. They are sensed via cell surface pattern-recognition receptors and are phagocytosed into newly formed organelles called phagosomes. Phagosomes mature through the recruitment of proteins and lysosomes, resulting in addition of p...

Full description

Bibliographic Details
Main Authors: Zeina Dagher, Shuying Xu, Paige E. Negoro, Nida S. Khan, Michael B. Feldman, Jennifer L. Reedy, Jenny M. Tam, David B. Sykes, Michael K. Mansour
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.01058/full