Octreotide (somatostatin analog) attenuates cardiac ischemia/reperfusion injury via activating nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling pathway in rat model of hyperthyroidism

Octreotide (somatostatin analog) attenuates cardiac ischemia/reperfusion injury via activating nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling pathway in rat model of hyperthyroidism

Abstract Background Hyperthyroidism is known to increase the risk of ischemic heart diseases. Octreotide has been reported to attenuate ischemia/reperfusion (I/R) injury. Whether it is useful when ischemic heart disease is accompanied with co-morbidities like hyperthyroidism needs more clarifying. S...

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Bibliographic Details
Main Authors: Randa Salah Gomaa, Nevertyty Mohamed Mahmoud, Nourelhuda Abdelaziz Mohammed
Format: Article
Language:English
Published: SpringerOpen 2020-10-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Hyperthyroidism
Myocardial ischemia/reperfusion injury
Nrf2
Octreotide
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s43094-020-00127-w

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http://link.springer.com/article/10.1186/s43094-020-00127-w

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