Icaritin protects against oxidative stress-induced injury in cardiac H9c2 cells via Akt/Nrf2/HO-1 and calcium signalling pathways

Icaritin protects against oxidative stress-induced injury in cardiac H9c2 cells via Akt/Nrf2/HO-1 and calcium signalling pathways

Icaritin, a prenylflavonoid isolated from Herbal Epimedii, is well known for its osteoplastic and anti-tumour activities. Here, we examined the cardioprotective actions of icaritin on cardiac H9c2 cells under oxidative stress conditions induced by treatment with tert-butylhydroperoxide (t-BHP). Icar...

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Bibliographic Details
Main Authors: Si Wan Lei, Guozhen Cui, George Pak Heng Leung, Sharon Chui Wah Luk, Maggie Pui Man Hoi, Liang Wang, Gail B. Mahady, Simon Ming Yuen Lee
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Icaritin
Cardiac H9c2 cells
Oxidative stress
NF-E2-related factor 2
Calcium ion
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615003485

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http://www.sciencedirect.com/science/article/pii/S1756464615003485

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