Cardiac Electrophysiological Effects of Light-Activated Chloride Channels

Cardiac Electrophysiological Effects of Light-Activated Chloride Channels

During the last decade, optogenetics has emerged as a paradigm-shifting technique to monitor and steer the behavior of specific cell types in excitable tissues, including the heart. Activation of cation-conducting channelrhodopsins (ChR) leads to membrane depolarization, allowing one to effectively...

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Bibliographic Details
Main Authors: Ramona A. Kopton, Jonathan S. Baillie, Sara A. Rafferty, Robin Moss, Callum M. Zgierski-Johnston, Sergey V. Prykhozhij, Matthew R. Stoyek, Frank M. Smith, Peter Kohl, T. Alexander Quinn, Franziska Schneider-Warme
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Physiology
Subjects:
heart
optogenetics
action potential
GtACR1
natural anion channelrhodopsin
zebrafish
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01806/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01806/full

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