Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice.

To determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring.Female C57BL6J mice were fed an obesogenic high fat diet (HF, 45% kcal fat) or standard chow (C, 21% kcal fat) pre-conception...

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Bibliographic Details
Main Authors: Christopher Torrens, Priya Ethirajan, Kimberley D Bruce, Felino R A Cagampang, Richard C M Siow, Mark A Hanson, Christopher D Byrne, Giovanni E Mann, Geraldine F Clough
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3515587?pdf=render