JunB regulates homeostasis and suppressive functions of effector regulatory T cells

JunB regulates homeostasis and suppressive functions of effector regulatory T cells

Regulatory T (Treg) cells need to be differentiated into effector Treg (eTreg), with the transcription factor IRF4 implicated during this process. Here the authors show that an AP-1 family transcription factor, JunB, is expressed in eTreg to promote the IRF4 transcription program, and regulate eTreg...

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Bibliographic Details
Main Authors: Shin-ichi Koizumi, Daiki Sasaki, Tsung-Han Hsieh, Naoyuki Taira, Nana Arakaki, Shinichi Yamasaki, Ke Wang, Shukla Sarkar, Hiroki Shirahata, Mio Miyagi, Hiroki Ishikawa
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07735-4

Internet

https://doi.org/10.1038/s41467-018-07735-4

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