Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages
Despite its possible therapeutic potential against COVID-19, the exact mechanism(s) by which palmitoylethanolamide (PEA) exerts its beneficial activity is still unclear. PEA has demonstrated analgesic, anti-allergic, and anti-inflammatory activities. Most of the anti-inflammatory properties of PEA a...
Main Authors: | Alessandro Del Re, Chiara Corpetti, Marcella Pesce, Luisa Seguella, Luca Steardo, Irene Palenca, Sara Rurgo, Barbara De Conno, Giovanni Sarnelli, Giuseppe Esposito |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/11/9/592 |
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