Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells.

Understanding the molecular pathways regulating cardiogenesis is crucial for the early diagnosis of heart diseases and improvement of cardiovascular disease. During normal mammalian cardiac development, collagen and calcium-binding EGF domain-1 (Ccbe1) is expressed in the first and second heart fiel...

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Bibliographic Details
Main Authors: Oriol Bover, Tiago Justo, Paulo N G Pereira, João Facucho-Oliveira, José M Inácio, José S Ramalho, Ibrahim J Domian, José António Belo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6169972?pdf=render