Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes

Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes

Objective: The effectiveness of bariatric surgery in restoring β-cell function has been described in type-2 diabetes (T2D) patients and animal models for years, whereas the mechanistic underpinnings are largely unknown. The possibility of vertical sleeve gastrectomy (VSG) to rescue far-progressed, c...

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Bibliographic Details
Main Authors: Lena Oppenländer, Subarna Palit, Kerstin Stemmer, Tobias Greisle, Michael Sterr, Ciro Salinno, Aimée Bastidas-Ponce, Annette Feuchtinger, Anika Böttcher, Ansarullah, Fabian J. Theis, Heiko Lickert
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Metabolism
Subjects:
Vertical sleeve gastrectomy
Type-2 diabetes
Beta-cell dedifferentiation
Beta-cell redifferentiation
Beta-cell function
scRNA-sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001770

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http://www.sciencedirect.com/science/article/pii/S2212877821001770

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