Engineered Livers for Infectious Diseases

Engineered liver systems come in a variety of platform models, from 2-dimensional cocultures of primary human hepatocytes and stem cell–derived progeny, to 3-dimensional organoids and humanized mice. Because of the species-specificity of many human hepatropic pathogens, these engineered systems have...

Full description

Bibliographic Details
Main Authors: Nil Gural, Liliana Mancio-Silva, Jiang He, Sangeeta N. Bhatia
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
3D
HBV
HCV
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17301601