Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

Abstract Background The underlying biological mechanisms through which epidemiologically defined breast cancer risk factors contribute to disease risk remain poorly understood. Identification of the molecular changes associated with cancer risk factors in normal tissues may aid in determining the ea...

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Bibliographic Details
Main Authors: Kevin C. Johnson, E. Andres Houseman, Jessica E. King, Brock C. Christensen
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Breast Cancer Research
Subjects:
Normal breast
DNA methylation
Aging
5mC
Risk factors
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Online Access:http://link.springer.com/article/10.1186/s13058-017-0873-y

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http://link.springer.com/article/10.1186/s13058-017-0873-y

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