The impact of varying cluster size in cross-sectional stepped-wedge cluster randomised trials

Abstract Background Cluster randomised trials with unequal sized clusters often have lower precision than with clusters of equal size. To allow for this, sample sizes are inflated by a modified version of the design effect for clustering. These inflation factors are valid under the assumption that r...

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Bibliographic Details
Main Authors: James Thomas Martin, Karla Hemming, Alan Girling
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-019-0760-6