Intercalated Disk Extracellular Nanodomain Expansion in Patients With Atrial Fibrillation

Intercalated Disk Extracellular Nanodomain Expansion in Patients With Atrial Fibrillation

Aims: Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous evidence in animal models suggests that the gap junction (GJ) adjacent nanodomain – perinexus – is a site capable of independent intercellular communication via ephaptic transmission. Perinexal expansion is associated w...

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Bibliographic Details
Main Authors: Tristan B. Raisch, Matthew S. Yanoff, Timothy R. Larsen, Mohammed A. Farooqui, D. Ryan King, Rengasayee Veeraraghavan, Robert G. Gourdie, Joseph W. Baker, William S. Arnold, Soufian T. AlMahameed, Steven Poelzing
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
atrial fibrillation
gap junctions
connexin43
perinexus
human
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00398/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00398/full

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