Identification and functional study of GATA4 gene regulatory variants in atrial septal defects

Abstract Background Congenital heart disease (CHD) is the leading cause of mortality from birth defects. In adult CHD patients with successful surgical repair, cardiac complications including heart failure develop at late stage, likely due to genetic causes. To date, many mutations in cardiac develo...

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Bibliographic Details
Main Authors: Dongchen Fan, Shuchao Pang, Jing Chen, Jiping Shan, Qianjin Cheng, Bo Yan
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-021-02136-w