Consistent ultra-long DNA sequencing with automated slow pipetting

Abstract Background Oxford Nanopore Technologies’ instruments can sequence reads of great length. Long reads improve sequence assemblies by unambiguously spanning repetitive elements of the genome. Sequencing reads of significant length requires the preservation of long DNA template molecules throug...

Full description

Bibliographic Details
Main Authors: Trent M. Prall, Emma K. Neumann, Julie A. Karl, Cecilia G. Shortreed, David A. Baker, Hailey E. Bussan, Roger W. Wiseman, David H. O’Connor
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07500-w