A re-analysis of the Cochrane Library data: the dangers of unobserved heterogeneity in meta-analyses.

Heterogeneity has a key role in meta-analysis methods and can greatly affect conclusions. However, true levels of heterogeneity are unknown and often researchers assume homogeneity. We aim to: a) investigate the prevalence of unobserved heterogeneity and the validity of the assumption of homogeneity...

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Bibliographic Details
Main Authors: Evangelos Kontopantelis, David A Springate, David Reeves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724681?pdf=render