Poor immune reconstitution in HIV-infected patients associates with high percentage of regulatory CD4+ T cells.

CD4(+) regulatory T cells (Tregs) are essential for the maintenance of the immune system's equilibrium, by dampening the activation of potential auto-reactive T cells and avoiding excessive immune activation. To correctly perform their function, Tregs must be maintained at the right proportion...

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Bibliographic Details
Main Authors: Ana Horta, Claudia Nobrega, Pedro Amorim-Machado, Vitor Coutinho-Teixeira, Palmira Barreira-Silva, Susana Boavida, Patrício Costa, Rui Sarmento-Castro, António Gil Castro, Margarida Correia-Neves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577748?pdf=render