Epigenetic Memory: Lessons From iPS Cells Derived From Human β Cells

Incomplete reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) may be responsible for the heterogeneity in differentiation capacity observed among iPSC lines. It remains unclear whether it results from stochastic reprogramming events, or reflects consistent genetic or cell-of-...

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Bibliographic Details
Main Author: Shimon Efrat
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.614234/full