β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling

β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling

Background: Alzheimer's disease (AD), is a progressive neurodegenerative disease that is characterized by cognitive loss. Most researchers believe that aggregation and accumulation of β-amyloid peptides (Aβ) in brain cells are the central pathological hallmark of this disease.Methods: Based on...

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Bibliographic Details
Main Authors: Weiying Liu, Fengxian Sun, Moxin Wan, Fang Jiang, Xiangyu Bo, Laixiang Lin, Hua Tang, Shumei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer's disease
HPYD
β-amyloid peptides
APP
β-sheet breaker peptide
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00969/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00969/full

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