A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway

A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway

Abstract Background Tooth agenesis, one of the most common developmental anomalies, can affect the function and esthetics of patients. The aim of the present study was to identify genetic clues for familial tooth agenesis and explore the underlying mechanisms, focusing on the role of human dental pu...

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Bibliographic Details
Main Authors: Tianyi Xin, Ting Zhang, Qian Li, Tingting Yu, Yunyan Zhu, Ruili Yang, Yanheng Zhou
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Stem Cell Research & Therapy
Subjects:
MSX1
Odontogenesis
Stem cells
Erk pathway
Tooth agenesis
Online Access:http://link.springer.com/article/10.1186/s13287-018-0965-3

Internet

http://link.springer.com/article/10.1186/s13287-018-0965-3

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