Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation

Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation

Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth and proliferation. These metabolic alterations include (1) a shift from oxidative phosphorylation to aerobic glycolysis to support the increased need for ATP, (2) increased glutaminolysis for NADPH regeneratio...

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Bibliographic Details
Main Authors: Chelsea Schiliro, Bonnie L. Firestein
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Warburg Effect
cancer
oxidative phosphorylation
aerobic glycolysis
pentose phosphate pathway
one-carbon metabolism
Online Access:https://www.mdpi.com/2073-4409/10/5/1056

Internet

https://www.mdpi.com/2073-4409/10/5/1056

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