Experience-Dependent Effects of Muscimol-Induced Hippocampal Excitation on Mnemonic Discrimination

Memory requires similar episodes with overlapping features to be represented distinctly, a process that is disrupted in many clinical conditions as well as normal aging. Data from humans have linked this ability to activity in hippocampal CA3 and dentate gyrus (DG). While animal models have shown th...

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Bibliographic Details
Main Authors: Sarah A. Johnson, Sean M. Turner, Katelyn N. Lubke, Tara L. Cooper, Kaeli E. Fertal, Jennifer L. Bizon, Andrew P. Maurer, Sara N. Burke
Format: Article
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Systems Neuroscience
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2018.00072/full