RNA substrate length as an indicator of exosome interactions in vivo [version 1; referees: 2 approved, 1 approved with reservations]

Background: The exosome complex plays key roles in RNA processing and degradation in Eukaryotes and Archaea. Outstanding structural studies identified multiple pathways for RNA substrates into the exosome in vitro, but identifying the pathway followed by individual RNA species in vivo remains challe...

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Bibliographic Details
Main Authors: Clémentine Delan-Forino, Claudia Schneider, David Tollervey
Format: Article
Language:English
Published: Wellcome 2017-05-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/2-34/v1