Application of multi-SNP approaches Bayesian LASSO and AUC-RF to detect main effects of inflammatory-gene variants associated with bladder cancer risk.

Application of multi-SNP approaches Bayesian LASSO and AUC-RF to detect main effects of inflammatory-gene variants associated with bladder cancer risk.

The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer. We performed an association study between 886 inflammatory-gene variants and bladder cancer risk in 1,047 cases and 988 controls from the Spanish Bladder Cancer (SBC)/EPICURO Study....

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Bibliographic Details
Main Authors: Evangelina López de Maturana, Yuanqing Ye, M Luz Calle, Nathaniel Rothman, Víctor Urrea, Manolis Kogevinas, Sandra Petrus, Stephen J Chanock, Adonina Tardón, Montserrat García-Closas, Anna González-Neira, Gemma Vellalta, Alfredo Carrato, Arcadi Navarro, Belén Lorente-Galdós, Debra T Silverman, Francisco X Real, Xifeng Wu, Núria Malats
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877090?pdf=render

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