Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family

Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family

In humans and other vertebrate animals, vitamin K 2,3-epoxide reductase (VKOR) family enzymes are the gatekeepers between nutritionally acquired K vitamins and the vitamin K cycle responsible for posttranslational modifications that confer biological activity upon vitamin K-dependent proteins with c...

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Bibliographic Details
Main Authors: Carville G. Bevans, Christoph Krettler, Christoph Reinhart, Matthias Watzka, Johannes Oldenburg
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Nutrients
Subjects:
cyclic permutation
DsbB
homology modeling
phylogeny
sequence conservation
vitamin K
vitamin K 2,3-epoxide
VKOR
VKORC1
VKORC1L1
Online Access:http://www.mdpi.com/2072-6643/7/8/5281

Internet

http://www.mdpi.com/2072-6643/7/8/5281

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