A human PrM antibody that recognizes a novel cryptic epitope on dengue E glycoprotein.

A human PrM antibody that recognizes a novel cryptic epitope on dengue E glycoprotein.

Dengue virus (DENV) is a major mosquito-borne pathogen infecting up to 100 million people each year; so far no effective treatment or vaccines are available. Recently, highly cross-reactive and infection-enhancing pre-membrane (prM)-specific antibodies were found to dominate the anti-DENV immune res...

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Bibliographic Details
Main Authors: Annie Hoi Yi Chan, Hwee Cheng Tan, Angelia Yee Chow, Angeline Pei Chiew Lim, Shee Mei Lok, Nicole J Moreland, Subhash G Vasudevan, Paul A MacAry, Eng Eong Ooi, Brendon J Hanson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317930?pdf=render

Internet

http://europepmc.org/articles/PMC3317930?pdf=render

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