N-terminus three residues deletion mutant of human beta-defensin 3 with remarkably enhanced salt-resistance.

In this study, we designed and synthesized three N-terminal deletion analogs of human beta-defensin 3 (hBD-3), namely, hBD-3Δ4, hBD-3Δ7, and hBD-3Δ10, to determine the effect of N-terminal residues on the antibacterial activity and salt resistance of these peptides. The antibacterial activities and...

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Bibliographic Details
Main Authors: Tao Li, Feng Guo, Qin Wang, Huali Fang, Zhan Li, Dehui Wang, Hui Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4338079?pdf=render