Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients

Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients

Bipolar disorder (BD) is a progressive psychiatric disorder characterized by recurrent changes of mood and is associated with cognitive decline. There is evidence of excitotoxicity, neuroinflammation, upregulated arachidonic acid (AA) cascade signaling and brain atrophy in BD patients. These observa...

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Bibliographic Details
Main Authors: Hyung-Wook Kim, Stanley I. Rapoport, Jagadeesh S. Rao
Format: Article
Language:English
Published: Elsevier 2010-03-01
Series:Neurobiology of Disease
Subjects:
Bipolar disorder
Apoptosis
Caspase
BDNF
Synaptophysin
Drebrin
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109003325

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http://www.sciencedirect.com/science/article/pii/S0969996109003325

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