Complementary Role of P2 and Adenosine Receptors in ATP Induced-Anti-Apoptotic Effects Against Hypoxic Injury of HUVECs

Complementary Role of P2 and Adenosine Receptors in ATP Induced-Anti-Apoptotic Effects Against Hypoxic Injury of HUVECs

Background: Vascular endothelial injury during ischemia generates apoptotic cell death and precedes apoptosis of underlying tissues. We aimed at studying the role of extracellular adenosine triphosphate (ATP) on endothelial cells protection against hypoxia injury. Methods: In a hypoxic model on endo...

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Bibliographic Details
Main Authors: Catherine Feliu, Hélène Peyret, Gael Poitevin, Yoann Cazaubon, Floriane Oszust, Philippe Nguyen, Hervé Millart, Zoubir Djerada
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
endothelial cells
hypoxic stress
purinergic signaling
ATP
adenosine
Online Access:https://www.mdpi.com/1422-0067/20/6/1446

Internet

https://www.mdpi.com/1422-0067/20/6/1446

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