Role of Klf4 in the Regulation of Apoptosis and Cell Cycle in Rat Granulosa Cells during the Periovulatory Period

Role of Klf4 in the Regulation of Apoptosis and Cell Cycle in Rat Granulosa Cells during the Periovulatory Period

In the ovary, the luteinizing hormone (LH) surge suppresses the proliferation and induces the luteinization of preovulatory granulosa cells (GCs), which is crucial for the survival of terminally-differentiated GCs. Krüppel-like factor 4 (Klf4) has been shown to play a role in regulating the...

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Bibliographic Details
Main Authors: Hyeonhae Choi, Jaesook Roh
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
Klf4
granulosa cells
LH surge
apoptosis
cell cycle
Online Access:http://www.mdpi.com/1422-0067/20/1/87

Internet

http://www.mdpi.com/1422-0067/20/1/87

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