Proteomic Analysis of Mucopolysaccharidosis IIIB Mouse Brain

Proteomic Analysis of Mucopolysaccharidosis IIIB Mouse Brain

Mucopolysaccharidosis IIIB (MPS IIIB) is an inherited metabolic disease due to deficiency of α-N-Acetylglucosaminidase (NAGLU) enzyme with subsequent storage of undegraded heparan sulfate (HS). The main clinical manifestations of the disease are profound intellectual disability and neurodegeneration...

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Bibliographic Details
Main Authors: Valeria De Pasquale, Michele Costanzo, Rosa Anna Siciliano, Maria Fiorella Mazzeo, Valeria Pistorio, Laura Bianchi, Emanuela Marchese, Margherita Ruoppolo, Luigi Michele Pavone, Marianna Caterino
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
mucopolysaccharidosis iiib
quantitative proteomics
naglu
lysosomes
Online Access:https://www.mdpi.com/2218-273X/10/3/355

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https://www.mdpi.com/2218-273X/10/3/355

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