Mechanobiological Feedback in Pulmonary Vascular Disease

Mechanobiological Feedback in Pulmonary Vascular Disease

Vascular stiffening in the pulmonary arterial bed is increasingly recognized as an early disease marker and contributor to right ventricular workload in pulmonary hypertension. Changes in pulmonary artery stiffness throughout the pulmonary vascular tree lead to physiologic alterations in pressure an...

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Bibliographic Details
Main Authors: Paul B. Dieffenbach, Marcy Maracle, Daniel J. Tschumperlin, Laura E. Fredenburgh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
vascular stiffness
pulmonary arterial stiffness
pulmonary hypertension
mechanotransduction
cellular mechanosensors
YAP/TAZ
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00951/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00951/full

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