Redox-derived damage-associated molecular patterns: Ligand function of lipid peroxidation adducts
Endogenous electrophiles, such as α,β-unsaturated aldehydes and ketones generated during lipid peroxidation, exhibit a facile reactivity with proteins, generating a variety of intra and intermolecular covalent adducts. It has been postulated that these host-derived, modified proteins with electroph...
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Format: | Article |
Language: | English |
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Elsevier
2013-01-01
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Series: | Redox Biology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231712000201 |