ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells
Summary: Cardiac development requires coordinated biphasic regulation of the WNT/β-catenin signaling pathway. By intersecting gene expression and loss-of-function siRNA screens we identified Alpha Protein Kinase 2 (ALPK2) as a candidate negative regulator of WNT/β-catenin signaling in cardiogenesis....
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-04-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004218300191 |