Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice.

Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice.

The interaction between atherosclerosis and commensal microbes through leaky gut syndrome (LGS), which is characterized by impaired intestinal permeability and the introduction of undesired pathogens into the body, has not been fully elucidated. Our aim was to investigate the potential role of a ClC...

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Bibliographic Details
Main Authors: Kentaro Arakawa, Tomoaki Ishigami, Michiko Nakai-Sugiyama, Lin Chen, Hiroshi Doi, Tabito Kino, Shintaro Minegishi, Sae Saigoh-Teranaka, Rie Sasaki-Nakashima, Kiyoshi Hibi, Kazuo Kimura, Kouichi Tamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218096

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https://doi.org/10.1371/journal.pone.0218096

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