Extent of structural asymmetry in homodimeric proteins: prevalence and relevance.

Most homodimeric proteins have symmetric structure. Although symmetry is known to confer structural and functional advantage, asymmetric organization is also observed. Using a non-redundant dataset of 223 high-resolution crystal structures of biologically relevant homodimers, we address questions on...

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Bibliographic Details
Main Authors: Lakshmipuram Seshadri Swapna, Kuchi Srikeerthana, Narayanaswamy Srinivasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3358323?pdf=render