Advances in Universal CAR-T Cell Therapy

Advances in Universal CAR-T Cell Therapy

Chimeric antigen receptor T (CAR-T) cell therapy achieved extraordinary achievements results in antitumor treatments, especially against hematological malignancies, where it leads to remarkable, long-term antineoplastic effects with higher target specificity. Nevertheless, some limitations persist i...

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Bibliographic Details
Main Authors: Haolong Lin, Jiali Cheng, Wei Mu, Jianfeng Zhou, Li Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
cellular immunotherapy
chimeric antigen receptor T cell therapy
universal chimeric antigen receptor T cell therapy
gene editing
CRISPR/Cas9
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.744823/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.744823/full

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