Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib

Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib

Shiga toxin producing Escherichia coli (STEC) are a major cause of food-borne illness worldwide. However, a consensus regarding the role Shiga toxins play in the onset of diarrhea and hemorrhagic colitis is lacking. One of the obstacles to understanding the role of Shiga toxins to STEC-mediated inte...

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Bibliographic Details
Main Authors: Samuel eStone, Cheleste eThorpe, Amrita eAhluwalia, Arlin eRogers, Fumiko eObata, Aimee eVozenilek, Glynis eKolling, Anne eKane, Bruce eMagun, Dakshina eJandhyala
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Colon
Inflammation
Shiga Toxin
rabbit
Imatinib
p38
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00135/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00135/full

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