Rapid response of brain metastasis to crizotinib in a patient with KLC1-ALK fusion and MET gene amplification positive non-small cell lung cancer: a case report

Rapid response of brain metastasis to crizotinib in a patient with KLC1-ALK fusion and MET gene amplification positive non-small cell lung cancer: a case report

Non-small cell lung cancer (NSCLC) ranks as the leading cause of cancer-related death in the world. Brain metastasis (BM) is a common complication of NSCLC, with 25%–40% of patients developing BM during the course of the disease. A significant strategy of local disease control in the central nervous...

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Bibliographic Details
Main Authors: Peng Wang, Pei Xiao, Yingnan Ye, Pengpeng Liu, Lei Han, Li Dong, Chunhua She, Jinpu Yu
Format: Article
Language:English
Published: China Anti-Cancer Association 2017-03-01
Series:Cancer Biology & Medicine
Subjects:
NSCLC
precision medicine
KLC1-ALK fusion
MET amplification
next-generation sequencing
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1033

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1033

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