HSQC-TOCSY Fingerprinting-Directed Discovery of Antiplasmodial Polyketides from the Marine Ascidian-Derived Streptomyces sp. (USC-16018)

HSQC-TOCSY Fingerprinting-Directed Discovery of Antiplasmodial Polyketides from the Marine Ascidian-Derived Streptomyces sp. (USC-16018)

Chemical investigations on the fermentation extract obtained from an ascidian-derived Streptomyces sp. (USC-16018) yielded a new ansamycin polyketide, herbimycin G (1), as well as a known macrocyclic polyketide, elaiophylin (2), and four known diketopiperazines (3–6). The structures of the...

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Bibliographic Details
Main Authors: Larissa Buedenbender, Luke P. Robertson, Leonardo Lucantoni, Vicky M. Avery, D. İpek Kurtböke, Anthony R. Carroll
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Marine Drugs
Subjects:
actinomycetes
Streptomyces
ascidian-associated actinomycetes
Symplegma rubra
polyketide
ansamycin derivative
herbimycin
antiplasmodial activity
Online Access:http://www.mdpi.com/1660-3397/16/6/189

Internet

http://www.mdpi.com/1660-3397/16/6/189

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