Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

Abstract Background Classification of COPD is usually based on the severity of airflow, which may not sensitively differentiate subpopulations. Using a multiscale imaging-based cluster analysis (MICA), we aim to identify subpopulations for current smokers with COPD. Methods Among the SPIROMICS subje...

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Bibliographic Details
Main Authors: Babak Haghighi, Sanghun Choi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell, R. Graham Barr, Eugene Bleecker, Christopher B. Cooper, David Couper, Mei Lan Han, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, Eric A. C. Kleerup, Fernando J. Martinez, Wanda O’Neal, Stephen I. Rennard, Prescott G. Woodruff, Ching-Long Lin
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Respiratory Research
Subjects:
COPD
Current smokers
Emphysema
Functional small airway disease
Imaging-based cluster analysis
Online Access:http://link.springer.com/article/10.1186/s12931-018-0888-7

Internet

http://link.springer.com/article/10.1186/s12931-018-0888-7

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