Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart.

Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart.

Executioner caspase-3 and -7 are proteases promoting cell death but non-apoptotic roles are being discovered. The heart expresses caspases only during development, suggesting they contribute to the organ maturation process. Therefore, we aimed at identifying novel functions of caspases in heart deve...

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Bibliographic Details
Main Authors: Maria Cardona, Juan Antonio López, Anna Serafín, Anthony Rongvaux, Javier Inserte, David García-Dorado, Richard Flavell, Marta Llovera, Xavier Cañas, Jesús Vázquez, Daniel Sanchis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4487935?pdf=render

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http://europepmc.org/articles/PMC4487935?pdf=render

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