Targeting pannexin1 improves seizure outcome.

Imbalance of the excitatory neurotransmitter glutamate and of the inhibitory neurotransmitter GABA is one of several causes of seizures. ATP has also been implicated in epilepsy. However, little is known about the mechanisms involved in the release of ATP from cells and the consequences of the alter...

Full description

Bibliographic Details
Main Authors: Marcelo F Santiago, Jana Veliskova, Naman K Patel, Sarah E Lutz, Dorothee Caille, Anne Charollais, Paolo Meda, Eliana Scemes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3175002?pdf=render