Aging- and Senescence-associated Changes of Mesenchymal Stromal Cells in Myelodysplastic Syndromes

Hematopoietic stem and progenitor cells reside within the bone marrow (BM) microenvironment. By a well-balanced interplay between self-renewal and differentiation, they ensure a lifelong supply of mature blood cells. Physiologically, multiple different cell types contribute to the regulation of stem...

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Bibliographic Details
Main Authors: Domenico Mattiucci, Giulia Maurizi, Pietro Leoni, Antonella Poloni
Format: Article
Language:English
Published: SAGE Publishing 2018-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689717745890