Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease

Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease

Summary: Despite the emerging evidence implying early vascular contributions to neurodegenerative syndromes, the role of vascular smooth muscle cells (VSMCs) in the pathogenesis of Alzheimer disease (AD) is still not well understood. Herein, we show that VSMCs in brains of patients with AD and anima...

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Bibliographic Details
Main Authors: Jorge A. Aguilar-Pineda, Karin J. Vera-Lopez, Pallavi Shrivastava, Miguel A. Chávez-Fumagalli, Rita Nieto-Montesinos, Karla L. Alvarez-Fernandez, Luis D. Goyzueta Mamani, Gonzalo Davila Del-Carpio, Badhin Gomez-Valdez, Clint L. Miller, Rajeev Malhotra, Mark E. Lindsay, Christian L. Lino Cardenas
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Molecular neuroscience
Immunology
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009615

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221009615

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