Avirulent Marek's disease virus type 1 strain 814 vectored vaccine expressing avian influenza (AI) virus H5 haemagglutinin induced better protection than turkey herpesvirus vectored AI vaccine.

Avirulent Marek's disease virus type 1 strain 814 vectored vaccine expressing avian influenza (AI) virus H5 haemagglutinin induced better protection than turkey herpesvirus vectored AI vaccine.

BACKGROUND: Herpesvirus of turkey (HVT) as a vector to express the haemagglutinin (HA) of avian influenza virus (AIV) H5 was developed and its protection against lethal Marek's disease virus (MDV) and highly pathogenic AIV (HPAIV) challenges was evaluated previously. It is well-known that aviru...

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Bibliographic Details
Main Authors: Hongyu Cui, Hongbo Gao, Xianlan Cui, Yan Zhao, Xingming Shi, Qiaoling Li, Shuai Yan, Ming Gao, Mei Wang, Changjun Liu, Yunfeng Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3536743?pdf=render

Internet

http://europepmc.org/articles/PMC3536743?pdf=render

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