Provir/Latitude 45 study: A step towards a multi-epitopic CTL vaccine designed on archived HIV-1 DNA and according to dominant HLA I alleles.

One of the approaches by which the scientific community is seeking to cure HIV is the use of therapeutic vaccination. Previous studies have highlighted the importance of the virus-specific CD8+ T cell cytotoxic responses for the immune control of HIV and have oriented research on vaccine constructs...

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Bibliographic Details
Main Authors: Camille Tumiotto, Bruna M Alves, Patricia Recordon-Pinson, Marine Jourdain, Pantxika Bellecave, Gwenda-Line Guidicelli, Jonathan Visentin, Fabrice Bonnet, Mojdan Hessamfar, Didier Neau, Jorge Sanchez, Christian Brander, Mohammad Sajadi, Lindsay Eyzaguirre, Esmeralda A Soares, Jean-Pierre Routy, Marcelo A Soares, Hervé Fleury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212347