Targeted disruption of the mouse testis-enriched gene Znf230 does not affect spermatogenesis or fertility

The mouse testis-enriched Znf230 gene, which encodes a type of RING finger protein, is present primarily in the nuclei of spermatogonia, the acrosome and the tail of spermatozoa. To investigate the role of Znf230 in spermatogenesis, we generated Znf230-deficient mice by disrupting Znf230 exon-5 and...

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Bibliographic Details
Main Authors: Yunqiang Liu, Dachang Tao, Yongjie Lu, Yuan Yang, Yongxin Ma, Sizhong Zhang
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2014-12-01
Series:Genetics and Molecular Biology
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000500014&lng=en&tlng=en