Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway.

Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway.

Oxidative stress plays an important role in the pathogenesis of neurodegenerative diseases, such as Parkinson's disease. The molecule, 2,3,5,4'-tetrahydr- oxystilbene-2-O-β-D-glucoside (TSG), is a potent antioxidant derived from the Chinese herb, Polygonum multiflorum Thunb. In this study,...

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Bibliographic Details
Main Authors: Lizhen Tao, Xiaofeng Li, Lingling Zhang, Jiyu Tian, Xiaobing Li, Xin Sun, Xuefen Li, Lin Jiang, Xiaojun Zhang, Jianzong Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3188584?pdf=render

Internet

http://europepmc.org/articles/PMC3188584?pdf=render

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