The focal adhesion protein Integrin-Linked Kinase (ILK) as an important player in breast cancer pathogenesis

The focal adhesion protein Integrin-Linked Kinase (ILK) as an important player in breast cancer pathogenesis

Cell-extracellular matrix interactions, or focal adhesions (FA), are crucial for tissue homeostasis but are also implicated in cancer. Integrin-Linked Kinase (ILK) is an abundantly expressed FA protein involved in multiple signaling pathways. Here, we reviewed the current literature on the role of I...

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Bibliographic Details
Main Authors: Katerina Tsirtsaki, Vasiliki Gkretsi
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cell Adhesion & Migration
Subjects:
breast cancer
metastasis
invasion
ilk
pinch-1
parva
rictor
akt
emt
focal adhesions
Online Access:http://dx.doi.org/10.1080/19336918.2020.1829263

Internet

http://dx.doi.org/10.1080/19336918.2020.1829263

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